生物化学与分子生物学

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蒋茂荣

日期:2023-08-02   点击数:15  

姓名:蒋茂荣     职称:副教授  

个人简介

男,江苏姜堰,博士研究生


专业研究领域

1.神经再生分子机制;2.神经炎症与神经保护;3.衰老与神经再生;4.人类疾病动物模型

专著与论集

1. 科学出版社,《神经生物学》

学术论文

1. Yumei Feng, Jian Shao, Min Cai, Yiyue Zhou, Yi Yao, Jiaxi Qian, Zihan Ding, Maorong Jiang, Dengbing Yao. Long noncoding RNA H19 regulates degeneration and regeneration of injured peripheral nerves. Neural Regen Res. 2023,18(8):1847-1851.

2. Lei Qian, Ming Li, Xin Lin, Hongwei Teng, Lulu Yu, Maorong Jiang. Interleukin-35 attenuates blood-brain barrier dysfunction caused by cerebral ischemia-reperfusion injury through inhibiting brain endothelial cell injury. Ann Transl Med. 2022, 10(14):776. (通讯作者)

3. Qianqian Ju, Maorong Jiang, Wenxin Huang, Qingbo Yang, Zhenghong Luo, Hui Shi. CtBP2 interacts with TGIF to promote the progression of esophageal squamous cell cancer through the Wnt/β‑catenin pathway. Oncol Rep. 2022, 47(2):29.

3. Qiang Zhao, Yuntian Shen, Ran Li, Jiangbo Wu, Jingjun Lyu, Maorong Jiang, Liping Lu, Minghua Zhu, Wei Wang, Zhuoran Wang, Qiang Liu, Ulrike Hoffmann, Jörn Karhausen, Huaxin Sheng, Weiguo Zhang, Wei Yang. Cardiac arrest and resuscitation activates the hypothalamic-pituitary-adrenal axis and results in severe immunosuppression. J Cereb Blood Flow Metab. 2021, 41(5):1091-1102.

4. Jiaqi Li, Maorong Jiang, JiaoRui Zhou, Junjie Ding, Zhimou Guo, Ming Li, Fei Ding, Wengang Chai, Jingyu Yan, Xinmiao Liang. Characterization of rat and mouse acidic milk oligosaccharides based on hydrophilic interaction chromatography coupled with electrospray tandem mass spectrometry. Carbohydr Polym. 2021, 259:117734. (共同第一作者)

5. Maorong Jiang, Ran Li, Jingjun Lyu, Xuan Li, Wei Wang, Zhuoran Wang, Huaxin Sheng, Weiguo Zhang, Jörn Karhausen, Wei Yang. MCC950, a selective NLRP3 inflammasome inhibitor, improves neurologic function and survival after cardiac arrest and resuscitation. J Neuroinflammation. 2020, 31;17(1):256. (第一作者)

6. Maorong Jiang, Hui Shi, Yunzhao Xu, Wen Bai, Peiwen Wang, Qianqian Ju. miR-203a-3p regulates the cellular processes of esophageal cancer cells via targeting CtBP2. Transl Cancer Res. 2019, 8(8):2791-2802. (第一作者)

7. Yingcheng Wu, Qianqian Ju, Keren Jia, Jingyan Yu, Hui Shi, Huiqun Wu, Maorong Jiang. Correlation between sex and efficacy of immune checkpoint inhibitors (PD-1 and CTLA-4 inhibitors). Int J Cancer. 2018, 143(1):45-51. (通讯作者)

7. Hui Shi, Yinting Mao, Qianqian Ju, Yingcheng Wu, Wen Bai, Peiwen Wang, Yudong Zhang, Maorong Jiang. C-terminal binding protein‑2 mediates cisplatin chemoresistance in esophageal cancer cells via the inhibition of apoptosis. Int J Oncol. 2018, 53(1):167-176. (通讯作者)

8. Hui Shi, Feng Yu, Yinting Mao, Qianqian Ju, Yingcheng Wu, Wen Bai, Peiwen Wang, Ran Xu, Maorong Jiang, Jiahai Shi. EphA2 chimeric antigen receptor-modified T cells for the immunotherapy of esophageal squamous cell carcinoma. J Thorac Dis. 2018, 10(5):2779-2788. (通讯作者)

9. Hui Shi, Jiahai Shi, Yudong Zhang, Chengqi Guan, Jun Zhu, Fei Wang, Mingming Xu, Qianqian Ju, Shu Fang, Maorong Jiang. Long non-coding RNA DANCR promotes cell proliferation, migration, invasion and resistance to apoptosis in esophageal cancer. J Thorac Dis. 2018, 10(5):2573-2582. (通讯作者)

10. Maorong Jiang, Qiong Cheng, Wenfeng Su, Caiping Wang, Yuming Yang, Zheng Cao, Fei Ding. The beneficial effect of chitooligosaccharides on cell behavior and function of primary Schwann cells is accompanied by up-regulation of adhesion proteins and neurotrophins. Neurochem Res. 2014, 39(11):2047-57. (第一作者)

11. Maorong Jiang, Zhimou Guo, Caiping Wang, Yuming Yang, Xinmiao Liang, Fei Ding. Neural activity analysis of pure chito-oligomer components separated from a mixture of chitooligosaccharides. Neurosci Lett. 2014, 581:32-6. (第一作者)

12. Maorong Jiang, Xiaoming Zhuge, Yumin Yang, Xiaosong Gu, Fei Ding. The promotion of peripheral nerve regeneration by chitooligosaccharides in the rat nerve crush injury model. Neurosci Lett. 2009, 454(3):239-43. (第一作者)

13. Maorong Jiang, Xiaosong Gu, Xiao Feng, Zheng Fan, Fei Ding, Yan Liu. The molecular characterization of the brain protein 44-like (Brp44l) gene of Gekko japonicus and its expression changes in spinal cord after tail amputation. Mol Biol Rep. 2009, 36(2):215-20. (第一作者)

 

主要科研项目 

1. 2012-2014:国家自然科学基金-青年项目

2. 2015-2018:江苏省自然科学基金-面上项目


讲授课程 

1.《分子生物学》

2.《生物化学》


指导研究生情况

现指导硕士研究生4